ADIPOR1 is essential for vision and its RPE expression is lost in the Mfrp(rd6) mouse

The knockout (KO) of the adiponectin receptor 1 (AdipoR1) gene causes retinal degeneration. Here we report that ADIPOR1 protein is primarily found in the eye and brain with little expression in other tissues. Further analysis of AdipoR1 KO mice revealed that these animals exhibit early visual system...

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Detalles Bibliográficos
Autores principales: Sluch, Valentin M., Banks, Angela, Li, Hui, Crowley, Maura A., Davis, Vanessa, Xiang, Chuanxi, Yang, Junzheng, Demirs, John T., Vrouvlianis, Joanna, Leehy, Barrett, Hanks, Shawn, Hyman, Alexandra M., Aranda, Jorge, Chang, Bo, Bigelow, Chad E., Rice, Dennis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156493/
https://www.ncbi.nlm.nih.gov/pubmed/30254279
http://dx.doi.org/10.1038/s41598-018-32579-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156493/
https://www.ncbi.nlm.nih.gov/pubmed/30254279
http://dx.doi.org/10.1038/s41598-018-32579-9

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