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Elimination of p19(ARF)‐expressing cells protects against pulmonary emphysema in mice

Senescent cells accumulate in tissues during aging and are considered to underlie several aging‐associated phenotypes and diseases. We recently reported that the elimination of p19(ARF)‐expressing senescent cells from lung tissue restored tissue function and gene expression in middle‐aged (12‐month‐...

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Detalles Bibliográficos
Autores principales: Mikawa, Ryuta, Suzuki, Yohei, Baskoro, Hario, Kanayama, Kazuki, Sugimoto, Kazushi, Sato, Tadashi, Sugimoto, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156494/
https://www.ncbi.nlm.nih.gov/pubmed/30058137
http://dx.doi.org/10.1111/acel.12827