Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging

Aging is characterized by a gradual functional decline of tissues with age. Adult stem and progenitor cells are responsible for tissue maintenance, repair, and regeneration, but during aging, this population of cells is decreased or its activity is reduced, compromising tissue integrity and causing...

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Detalles Bibliográficos
Autores principales: Vilas, Jéssica M., Carneiro, Carmen, Da Silva‐Álvarez, Sabela, Ferreirós, Alba, González, Patricia, Gómez, María, Ortega, Sagrario, Serrano, Manuel, García‐Caballero, Tomás, González‐Barcia, Miguel, Vidal, Anxo, Collado, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156495/
https://www.ncbi.nlm.nih.gov/pubmed/30129215
http://dx.doi.org/10.1111/acel.12834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156495/
https://www.ncbi.nlm.nih.gov/pubmed/30129215
http://dx.doi.org/10.1111/acel.12834

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