Cargando…

An OB-fold complex controls the repair pathways for DNA double-strand breaks

53BP1 with its downstream proteins, RIF1, PTIP and REV7, antagonizes BRCA1-dependent homologous recombination (HR) and promotes non-homologous end joining (NHEJ) in an unclear manner. Here we show that REV7 forms a complex with two proteins, FAM35A and C20ORF196. We demonstrate that FAM35A preferent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Shengxian, Feng, Sumin, Ning, Shaokai, Liu, Jingyan, Zhao, Huayu, Xu, Yixi, Shang, Jinfeng, Li, Kejiao, Li, Qing, Guo, Rong, Xu, Dongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156606/ https://www.ncbi.nlm.nih.gov/pubmed/30254264 http://dx.doi.org/10.1038/s41467-018-06407-7

Ejemplares similares

RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity
por: Feng, Sumin, et al.
Publicado: (2022)

Nampt is involved in DNA double-strand break repair
por: Zhu, Bingtao, et al.
Publicado: (2012)

The formation and repair of DNA double-strand breaks in mammalian meiosis
por: Qu, Wei, et al.
Publicado: (2021)

Repair of DNA Double-Strand Breaks in Heterochromatin
por: Watts, Felicity Z.
Publicado: (2016)

Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability
por: Terasawa, Masahiro, et al.
Publicado: (2014)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

DNA double-strand break repair in Caenorhabditis elegans
por: Lemmens, Bennie B. L. G., et al.
Publicado: (2010)

Phosphorylation: The Molecular Switch of Double-Strand Break Repair
por: Summers, K. C., et al.
Publicado: (2011)

The Chromatin Response to Double-Strand DNA Breaks and Their Repair
por: Aleksandrov, Radoslav, et al.
Publicado: (2020)

The Role of Noncoding RNAs in Double-Strand Break Repair
por: Durut, Nathalie, et al.
Publicado: (2019)

The roles of RNA in DNA double-strand break repair
por: Bader, Aldo S., et al.
Publicado: (2020)

ATM’s Role in the Repair of DNA Double-Strand Breaks
por: Shibata, Atsushi, et al.
Publicado: (2021)

Beta HPV Deregulates Double-Strand Break Repair
por: Hu, Changkun, et al.
Publicado: (2022)

Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair
por: Johnson, Rebecca, et al.
Publicado: (2007)

DNA Double-Strand Break Repairs and Their Application in Plant DNA Integration
por: Shen, Hexi, et al.
Publicado: (2022)

Role of Elg1 protein in double strand break repair
por: Ogiwara, Hideaki, et al.
Publicado: (2007)

DNA double-strand break repair and the evolution of intron density
por: Farlow, Ashley, et al.
Publicado: (2011)

Erratum to: DNA double-strand break repair in Caenorhabditis elegans
por: Lemmens, Bennie B. L. G., et al.
Publicado: (2011)

Chromatin modifications and DNA repair: beyond double-strand breaks
por: House, Nealia C. M., et al.
Publicado: (2014)

FKBP25 participates in DNA double-strand break repair()
por: Dilworth, David, et al.
Publicado: (2019)

Harnessing DNA Double-Strand Break Repair for Cancer Treatment
por: Trenner, Anika, et al.
Publicado: (2019)

Meiotic Genes and DNA Double Strand Break Repair in Cancer
por: Lingg, Lea, et al.
Publicado: (2022)

Histone acetylation dynamics in repair of DNA double-strand breaks
por: Aricthota, Shalini, et al.
Publicado: (2022)

WASH interacts with Ku to regulate DNA double-stranded break repair
por: Wang, Tao, et al.
Publicado: (2021)

Involvement of Nucleotide Excision and Mismatch Repair Mechanisms in Double Strand Break Repair
por: Zhang, Ye, et al.
Publicado: (2009)

Mu Insertions Are Repaired by the Double-Strand Break Repair Pathway of Escherichia coli
por: Jang, Sooin, et al.
Publicado: (2012)

Double-strand break repair processes drive evolution of the mitochondrial genome in Arabidopsis
por: Davila, Jaime I, et al.
Publicado: (2011)

Multiple-Pathway Analysis of Double-Strand Break Repair Mutations in Drosophila
por: Johnson-Schlitz, Dena M, et al.
Publicado: (2007)

c-Abl downregulates the slow phase of double-strand break repair
por: Meltser, V, et al.
Publicado: (2010)

Targeting the DNA Double Strand Break Repair Machinery in Prostate Cancer
por: Shaheen, Fadhel S., et al.
Publicado: (2011)

The Contribution of Alu Elements to Mutagenic DNA Double-Strand Break Repair
por: Morales, Maria E., et al.
Publicado: (2015)

Bora Downregulation Results in Radioresistance by Promoting Repair of Double Strand Breaks
por: Cairns, Junmei, et al.
Publicado: (2015)

RPA Antagonizes Microhomology-Mediated Repair of DNA Double-Strand Breaks
por: Deng, Sarah K, et al.
Publicado: (2014)

Genome plasticity is governed by double strand break DNA repair in Streptomyces
por: Hoff, Grégory, et al.
Publicado: (2018)

SUMO, a small, but powerful, regulator of double-strand break repair
por: Garvin, Alexander J., et al.
Publicado: (2017)

Regulation of DNA Double-Strand Break Repair by Non-Coding RNAs
por: Thapar, Roopa
Publicado: (2018)

Role of the double-strand break repair pathway in the maintenance of genomic stability
por: Le Guen, Tangui, et al.
Publicado: (2014)

Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
por: Lama-Sherpa, Tshering D, et al.
Publicado: (2020)

Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair
por: Borsos, Barbara N., et al.
Publicado: (2020)

The Role of Small Noncoding RNA in DNA Double-Strand Break Repair
por: Rzeszutek, Iwona, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bja4tqo43ij8a24gbdq4rpaj1p