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Simultaneous polymerization and adhesion under hypoxia in sickle cell disease

Polymerization and adhesion, dynamic processes that are hallmarks of sickle cell disease (SCD), have thus far been studied in vitro only separately. Here, we present quantitative results of the simultaneous and synergistic effects of adhesion and polymerization of deoxygenated sickle hemoglobin (HbS...

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Detalles Bibliográficos
Autores principales: Papageorgiou, Dimitrios P., Abidi, Sabia Z., Chang, Hung-Yu, Li, Xuejin, Kato, Gregory J., Karniadakis, George E., Suresh, Subra, Dao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156668/
https://www.ncbi.nlm.nih.gov/pubmed/30190429
http://dx.doi.org/10.1073/pnas.1807405115