Mechanics of diseased red blood cells in human spleen and consequences for hereditary blood disorders

In red blood cell (RBC) diseases, the spleen contributes to anemia by clearing the damaged RBCs, but its unique ability to mechanically challenge RBCs also poses the risk of inducing other pathogenic effects. We have analyzed RBCs in hereditary spherocytosis (HS) and hereditary elliptocytosis (HE),...

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Detalles Bibliográficos
Autores principales: Li, He, Lu, Lu, Li, Xuejin, Buffet, Pierre A., Dao, Ming, Karniadakis, George E., Suresh, Subra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156670/
https://www.ncbi.nlm.nih.gov/pubmed/30190436
http://dx.doi.org/10.1073/pnas.1806501115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156670/
https://www.ncbi.nlm.nih.gov/pubmed/30190436
http://dx.doi.org/10.1073/pnas.1806501115

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