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Capturing functional long non-coding RNAs through integrating large-scale causal relations from gene perturbation experiments

Characterizing functions of long noncoding RNAs (lncRNAs) remains a major challenge, mostly due to the lack of lncRNA-involved regulatory relationships. A wide array of genome-wide expression profiles generated by gene perturbation have been widely used to capture causal links between perturbed gene...

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Detalles Bibliográficos
Autores principales: Xu, Jinyuan, Shi, Aiai, Long, Zhilin, Xu, Liwen, Liao, Gaoming, Deng, Chunyu, Yan, Min, Xie, Aiming, Luo, Tao, Huang, Jian, Xiao, Yun, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156711/
https://www.ncbi.nlm.nih.gov/pubmed/30177244
http://dx.doi.org/10.1016/j.ebiom.2018.08.050