Tissue-specific effects of targeted mutation of Mir29b1 in rats

BACKGROUND: miR-29 is a master regulator of extracellular matrix genes, but conflicting data on its anti-fibrotic effect have been reported. miR-29 improves nitric oxide (NO) production in arterioles by targeting Lypla1. Mir29b1 targeted mutation exacerbates hypertension in a model derived from the...

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Detalles Bibliográficos
Autores principales: Xue, Hong, Zhang, Guangyuan, Geurts, Aron M., Usa, Kristie, Jensen, David M., Liu, Yong, Widlansky, Michael E., Liang, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156712/
https://www.ncbi.nlm.nih.gov/pubmed/30120082
http://dx.doi.org/10.1016/j.ebiom.2018.08.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156712/
https://www.ncbi.nlm.nih.gov/pubmed/30120082
http://dx.doi.org/10.1016/j.ebiom.2018.08.016

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