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Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/β-catenin signaling

BACKGROUND: Androgen receptor (AR) plays a crucial role as a transcription factor in promoting the development of hepatocellular carcinoma (HCC) which is prone to aberrant chromatin modifications. However, the regulatory effects of AR on epigenetic mediators in HCC remain ill-defined. Enhancer of ze...

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Detalles Bibliográficos
Autores principales: Song, Haibin, Yu, Zhuo, Sun, Xuehua, Feng, Jun, Yu, Qi, Khan, Hanif, Zhu, Xiaojun, Huang, Lingying, Li, Man, Mok, Myth T.S., Cheng, Alfred S.L., Gao, Yueqiu, Feng, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156715/
https://www.ncbi.nlm.nih.gov/pubmed/30150059
http://dx.doi.org/10.1016/j.ebiom.2018.08.043