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Increased genomic instability following treatment with direct acting anti-hepatitis C virus drugs

Mixed Cryoglobulinemic Vasculitis (MCV) is a prominent extra-hepatic manifestation of Hepatitis C virus (HCV) infection. HCV has been reported to cause B-cell disorders and genomic instability. Here, we investigated B-cell activation and genome stability in HCV-MCV patients receiving the direct anti...

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Detalles Bibliográficos
Autores principales: Hegazy, Mohamed Tharwat, Allam, Walaa Ramadan, Hussein, Mohamed A., Zoheir, Naguib, Quartuccio, Luca, El-Khamisy, Sherif F., Ragab, Gaafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156732/
https://www.ncbi.nlm.nih.gov/pubmed/30139628
http://dx.doi.org/10.1016/j.ebiom.2018.08.007