Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate

Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells and was previously shown by us to elicit a stress response in Caenorhabditis elegans that, at lower concentrations, results in enhanced stress resistance and longer lifespan. This h...

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Detalles Bibliográficos
Autores principales: Gille, Andrea, Turkistani, Abdullah, Tsitsipatis, Dimitrios, Hou, Xiaoqing, Tauber, Sarah, Hamann, Ingrit, Urban, Nadine, Erler, Katrin, Steinbrenner, Holger, Klotz, Lars-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156746/
https://www.ncbi.nlm.nih.gov/pubmed/30261343
http://dx.doi.org/10.1016/j.redox.2018.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156746/
https://www.ncbi.nlm.nih.gov/pubmed/30261343
http://dx.doi.org/10.1016/j.redox.2018.09.010

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