Tissue‐resident memory T cells are epigenetically cytotoxic with signs of exhaustion in human urinary bladder cancer

Tissue‐resident memory T (T(RM)) cells are CD8(+) T lymphocytes that reside in the tissues, including tumours. This T cell subset possesses a magnitude of cytotoxicity, but its epigenetic regulation has not been studied. Here, we investigate the impact of perforin DNA methylation in T(RM) cells and...

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Detalles Bibliográficos
Autores principales: Hartana, C. A., Ahlén Bergman, E., Broomé, A., Berglund, S., Johansson, M., Alamdari, F., Jakubczyk, T., Huge, Y., Aljabery, F., Palmqvist, K., Holmström, B., Glise, H., Riklund, K., Sherif, A., Winqvist, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156818/
https://www.ncbi.nlm.nih.gov/pubmed/30009527
http://dx.doi.org/10.1111/cei.13183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156818/
https://www.ncbi.nlm.nih.gov/pubmed/30009527
http://dx.doi.org/10.1111/cei.13183

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