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Quality control for Illumina 450K methylation data in the absence of iDat files using correlation structure in pedigrees and repeated measures

BACKGROUND: An important feature in many genomic studies is quality control and normalization. This is particularly important when analyzing epigenetic data, where the process of obtaining measurements can be bias prone. The GAW20 data was from the Genetics of Lipid Lowering Drugs and Diet Network (...

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Detalles Bibliográficos
Autores principales: LeBlanc, Marissa, Nustad, Haakon E., Zucknick, Manuela, Page, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156833/
https://www.ncbi.nlm.nih.gov/pubmed/30255766
http://dx.doi.org/10.1186/s12863-018-0636-5