CRISPR/Cas9-mediated genome editing induces exon skipping by complete or stochastic altering splicing in the migratory locust

BACKGROUND: The CRISPR/Cas9 system has been widely used to generate gene knockout/knockin models by inducing frameshift mutants in cell lines and organisms. Several recent studies have reported that such mutants can lead to in-frame exon skipping in cell lines. However, there was little research abo...

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Detalles Bibliográficos
Autores principales: Chen, Dafeng, Tang, Ji-Xin, Li, Beibei, Hou, Li, Wang, Xianhui, Kang, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156852/
https://www.ncbi.nlm.nih.gov/pubmed/30253761
http://dx.doi.org/10.1186/s12896-018-0465-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156852/
https://www.ncbi.nlm.nih.gov/pubmed/30253761
http://dx.doi.org/10.1186/s12896-018-0465-7

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