The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells

BACKGROUND: Mounting evidence from genome-wide studies of cancer shows that chromatin-mediated epigenetic silencing at large cohorts of genes is strongly linked to a poor prognosis. This mechanism is thought to prevent cell differentiation and enable evasion of the immune system. Drugging the cancer...

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Detalles Bibliográficos
Autores principales: Olney, Kimberly C., Nyer, David B., Vargas, Daniel A., Wilson Sayres, Melissa A., Haynes, Karmella A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156859/
https://www.ncbi.nlm.nih.gov/pubmed/30253781
http://dx.doi.org/10.1186/s12918-018-0608-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156859/
https://www.ncbi.nlm.nih.gov/pubmed/30253781
http://dx.doi.org/10.1186/s12918-018-0608-4

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