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Comparison of novel and existing methods for detecting differentially methylated regions

BACKGROUND: Single-probe analyses in epigenome-wide association studies (EWAS) have identified associations between DNA methylation and many phenotypes, but do not take into account information from neighboring probes. Methods to detect differentially methylated regions (DMRs) (clusters of neighbori...

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Detalles Bibliográficos
Autores principales: Lent, Samantha, Xu, Hanfei, Wang, Lan, Wang, Zhe, Sarnowski, Chloé, Hivert, Marie-France, Dupuis, Josée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156895/
https://www.ncbi.nlm.nih.gov/pubmed/30255775
http://dx.doi.org/10.1186/s12863-018-0637-4