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Comparison of novel and existing methods for detecting differentially methylated regions
BACKGROUND: Single-probe analyses in epigenome-wide association studies (EWAS) have identified associations between DNA methylation and many phenotypes, but do not take into account information from neighboring probes. Methods to detect differentially methylated regions (DMRs) (clusters of neighbori...
Autores principales: | Lent, Samantha, Xu, Hanfei, Wang, Lan, Wang, Zhe, Sarnowski, Chloé, Hivert, Marie-France, Dupuis, Josée |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156895/ https://www.ncbi.nlm.nih.gov/pubmed/30255775 http://dx.doi.org/10.1186/s12863-018-0637-4 |
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