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Coping with family structure in genome-wide association studies: a comparative evaluation

In this paper, a fully statistical investigation of the control of family structure as random effects is analyzed and discussed, using both the genome-wide association studies (GWAS) data and simulated data. Three modeling strategies are proposed and the analysis results suggest the hybrid use of re...

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Detalles Bibliográficos
Autores principales: Hsu, Yayun, Auerbach, Jonathan, Zheng, Tian, Lo, Shaw-hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156900/
https://www.ncbi.nlm.nih.gov/pubmed/30263047
http://dx.doi.org/10.1186/s12919-018-0151-8