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Coping with family structure in genome-wide association studies: a comparative evaluation
In this paper, a fully statistical investigation of the control of family structure as random effects is analyzed and discussed, using both the genome-wide association studies (GWAS) data and simulated data. Three modeling strategies are proposed and the analysis results suggest the hybrid use of re...
Autores principales: | Hsu, Yayun, Auerbach, Jonathan, Zheng, Tian, Lo, Shaw-hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156900/ https://www.ncbi.nlm.nih.gov/pubmed/30263047 http://dx.doi.org/10.1186/s12919-018-0151-8 |
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