From mutations to mechanisms and dysfunction via computation and mining of protein energy landscapes

BACKGROUND: The protein energy landscape underscores the inherent nature of proteins as dynamic molecules interconverting between structures with varying energies. Reconstructing a protein’s energy landscape holds the key to characterizing a protein’s equilibrium conformational dynamics and its rela...

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Detalles Bibliográficos
Autores principales: Qiao, Wanli, Akhter, Nasrin, Fang, Xiaowen, Maximova, Tatiana, Plaku, Erion, Shehu, Amarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156908/
https://www.ncbi.nlm.nih.gov/pubmed/30255791
http://dx.doi.org/10.1186/s12864-018-5024-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156908/
https://www.ncbi.nlm.nih.gov/pubmed/30255791
http://dx.doi.org/10.1186/s12864-018-5024-z

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