Cargando…
From mutations to mechanisms and dysfunction via computation and mining of protein energy landscapes
BACKGROUND: The protein energy landscape underscores the inherent nature of proteins as dynamic molecules interconverting between structures with varying energies. Reconstructing a protein’s energy landscape holds the key to characterizing a protein’s equilibrium conformational dynamics and its rela...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156908/ https://www.ncbi.nlm.nih.gov/pubmed/30255791 http://dx.doi.org/10.1186/s12864-018-5024-z |