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Joint screening of ultrahigh dimensional variables for family-based genetic studies
BACKGROUND: Mixed models are a useful tool for evaluating the association between an outcome variable and genetic variables from a family-based genetic study, taking into account the kinship coefficients. When there are ultrahigh dimensional genetic variables (ie, p ≫ n), it is challenging to fit an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156922/ https://www.ncbi.nlm.nih.gov/pubmed/30263041 http://dx.doi.org/10.1186/s12919-018-0120-2 |