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Joint screening of ultrahigh dimensional variables for family-based genetic studies

BACKGROUND: Mixed models are a useful tool for evaluating the association between an outcome variable and genetic variables from a family-based genetic study, taking into account the kinship coefficients. When there are ultrahigh dimensional genetic variables (ie, p ≫ n), it is challenging to fit an...

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Detalles Bibliográficos
Autores principales: Datta, Subha, Fang, Yixin, Loh, Ji Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156922/
https://www.ncbi.nlm.nih.gov/pubmed/30263041
http://dx.doi.org/10.1186/s12919-018-0120-2