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Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships

The heritability of a phenotype is an estimation of the percent of variance in that phenotype that is attributable to additive genetic factors. Heritability is optimally estimated in family-based sample populations. Traditionally, this involves use of a pedigree-based kinship coefficient generated f...

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Detalles Bibliográficos
Autores principales: Blackburn, Nicholas B., Porto, Arthur, Peralta, Juan M., Blangero, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157025/
https://www.ncbi.nlm.nih.gov/pubmed/30263045
http://dx.doi.org/10.1186/s12919-018-0133-x