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Characterization of the contribution of shared environmental and genetic factors to metabolic syndrome methylation heritability and familial correlations

BACKGROUND: Transgenerational epigenetic inheritance has been posited as a possible contributor to the observed heritability of metabolic syndrome (MetS). Yet the extent to which estimates of epigenetic inheritance for DNA methylation sites are inflated by environmental and genetic covariance within...

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Detalles Bibliográficos
Autores principales: Fernández-Rhodes, Lindsay, Howard, Annie Green, Tao, Ran, Young, Kristin L., Graff, Mariaelisa, Aiello, Allison E., North, Kari E., Justice, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157030/
https://www.ncbi.nlm.nih.gov/pubmed/30255772
http://dx.doi.org/10.1186/s12863-018-0634-7