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Integrating epigenetic, genetic, and phenotypic data to uncover gene-region associations with triglycerides in the GOLDN study

BACKGROUND: There has been significant interest in investigating genome-wide and epigenome-wide associations with lipids. Testing at the gene or region level may improve power in such studies. METHODS: We analyze chromosome 11 cytosine-phosphate-guanine (CpG) methylation levels and single-nucleotide...

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Detalles Bibliográficos
Autores principales: Romanescu, Razvan G., Espin-Garcia, Osvaldo, Ma, Jin, Bull, Shelley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157034/
https://www.ncbi.nlm.nih.gov/pubmed/30263054
http://dx.doi.org/10.1186/s12919-018-0142-9