In silico read normalization using set multi-cover optimization

MOTIVATION: De Bruijn graphs are a common assembly data structure for sequencing datasets. But with the advances in sequencing technologies, assembling high coverage datasets has become a computational challenge. Read normalization, which removes redundancy in datasets, is widely applied to reduce r...

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Detalles Bibliográficos
Autores principales: Durai, Dilip A, Schulz, Marcel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157080/
https://www.ncbi.nlm.nih.gov/pubmed/29912280
http://dx.doi.org/10.1093/bioinformatics/bty307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157080/
https://www.ncbi.nlm.nih.gov/pubmed/29912280
http://dx.doi.org/10.1093/bioinformatics/bty307

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