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In silico read normalization using set multi-cover optimization
MOTIVATION: De Bruijn graphs are a common assembly data structure for sequencing datasets. But with the advances in sequencing technologies, assembling high coverage datasets has become a computational challenge. Read normalization, which removes redundancy in datasets, is widely applied to reduce r...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157080/ https://www.ncbi.nlm.nih.gov/pubmed/29912280 http://dx.doi.org/10.1093/bioinformatics/bty307 |