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An adaptive gene-based test for methylation data

DNA methylation plays an important role in normal human development and disease. In epigenome-wide association studies (EWAS), a univariate test for association between a phenotype and each cytosine-phosphate-guanine (CpG) site has been widely used. Given the number of CpG sites tested in EWAS, a st...

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Detalles Bibliográficos
Autores principales: Wu, Chong, Park, Jun Young, Guan, Weihua, Pan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157100/
https://www.ncbi.nlm.nih.gov/pubmed/30275902
http://dx.doi.org/10.1186/s12919-018-0126-9