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Relating drug response to epigenetic and genetic markers using a region-based kernel score test

In GAW20, we investigated the association of specific genetic regions of interest (ROIs) with log-transformed triglyceride (TG) levels following lipid-lowering medication using epigenetic and genetic markers. The goal was to incorporate kernels for cytosine-phosphate-guanine (CpG) markers and compar...

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Detalles Bibliográficos
Autores principales: Yasmeen, Summaira, Burger, Patricia, Friedrichs, Stefanie, Papiol, Sergi, Bickeböller, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157113/
https://www.ncbi.nlm.nih.gov/pubmed/30275895
http://dx.doi.org/10.1186/s12919-018-0154-5