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Relating drug response to epigenetic and genetic markers using a region-based kernel score test
In GAW20, we investigated the association of specific genetic regions of interest (ROIs) with log-transformed triglyceride (TG) levels following lipid-lowering medication using epigenetic and genetic markers. The goal was to incorporate kernels for cytosine-phosphate-guanine (CpG) markers and compar...
Autores principales: | Yasmeen, Summaira, Burger, Patricia, Friedrichs, Stefanie, Papiol, Sergi, Bickeböller, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157113/ https://www.ncbi.nlm.nih.gov/pubmed/30275895 http://dx.doi.org/10.1186/s12919-018-0154-5 |
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