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Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study

BACKGROUND: A prevalent side-effect of simvastatin is attenuated glucose homeostasis. The underlying mechanism is unknown, but impaired lipid metabolism may provide the link. The aim of this study was to investigate whether simvastatin-treated patients had a lower capacity to oxidize lipids and redu...

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Detalles Bibliográficos
Autores principales: Larsen, Steen, Vigelsø, Andreas, Dandanell, Sune, Prats, Clara, Dela, Flemming, Helge, Jørn Wulff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157137/
https://www.ncbi.nlm.nih.gov/pubmed/30276217
http://dx.doi.org/10.1155/2018/9257874