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Analysis of genotype by methylation interactions through sparsity-inducing regularized regression
In this paper, we consider the use of the least absolute shrinkage and selection operator (LASSO)-type regression techniques to detect important genetic or epigenetic loci in genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS). We demonstrate how these techniques can...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157158/ https://www.ncbi.nlm.nih.gov/pubmed/30275890 http://dx.doi.org/10.1186/s12919-018-0145-6 |