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Analysis of genotype by methylation interactions through sparsity-inducing regularized regression

In this paper, we consider the use of the least absolute shrinkage and selection operator (LASSO)-type regression techniques to detect important genetic or epigenetic loci in genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS). We demonstrate how these techniques can...

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Detalles Bibliográficos
Autores principales: Zhou, Wenda, Lo, Shaw-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157158/
https://www.ncbi.nlm.nih.gov/pubmed/30275890
http://dx.doi.org/10.1186/s12919-018-0145-6

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