Evidence of batch effects masking treatment effect in GAW20 methylation data

Using the real data set from GAW20, we examined changes in the distribution of DNA methylation before and after treatment. Paired analysis of differences in both mean and variance had grossly inflated type 1 error, suggesting either a very large number of changes across the entire epigenome or major...

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Detalles Bibliográficos
Autores principales: Canty, Angelo J., Paterson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157182/
https://www.ncbi.nlm.nih.gov/pubmed/30275884
http://dx.doi.org/10.1186/s12919-018-0129-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157182/
https://www.ncbi.nlm.nih.gov/pubmed/30275884
http://dx.doi.org/10.1186/s12919-018-0129-6

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