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SiRNA silencing efficacy prediction based on a deep architecture

BACKGROUND: Small interfering RNA (siRNA) can be used to post-transcriptional gene regulation by knocking down targeted genes. In functional genomics, biomedical research and cancer therapeutics, siRNA design is a critical research topic. Various computational algorithms have been developed to selec...

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Detalles Bibliográficos
Autores principales: Han, Ye, He, Fei, Chen, Yongbing, Liu, Yuanning, Yu, Helong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157246/
https://www.ncbi.nlm.nih.gov/pubmed/30255786
http://dx.doi.org/10.1186/s12864-018-5028-8