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Incorporating methylation genome information improves prediction accuracy for drug treatment responses

BACKGROUND: An accumulation of evidence has revealed the important role of epigenetic factors in explaining the etiopathogenesis of human diseases. Several empirical studies have successfully incorporated methylation data into models for disease prediction. However, it is still a challenge to integr...

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Detalles Bibliográficos
Autores principales: Xia, Xiaoxuan, Weng, Haoyi, Men, Ruoting, Sun, Rui, Zee, Benny Chung Ying, Chong, Ka Chun, Wang, Maggie Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157255/
https://www.ncbi.nlm.nih.gov/pubmed/30255773
http://dx.doi.org/10.1186/s12863-018-0644-5