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Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models

Leishmania biomarker discovery remains an important challenge that needs to be revisited in light of our increasing knowledge on parasite-specific biology, notably its genome instability. In the absence of classical transcriptional regulation in these early-branching eukaryotes, fluctuations in tran...

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Detalles Bibliográficos
Autores principales: Piel, Laura, Pescher, Pascale, Späth, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157315/
https://www.ncbi.nlm.nih.gov/pubmed/30283743
http://dx.doi.org/10.3389/fcimb.2018.00325