Long-Term Follow-Up of a Phase I/II Study of ProSavin, a Lentiviral Vector Gene Therapy for Parkinson's Disease

Parkinson's disease is typically treated with oral dopamine replacement therapies. However, long-term use is complicated by motor fluctuations from intermittent stimulation of dopamine receptors and off-target effects. ProSavin, a lentiviral vector based gene therapy that delivers local and con...

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Detalles Bibliográficos
Autores principales: Palfi, Stéphane, Gurruchaga, Jean Marc, Lepetit, Hélène, Howard, Katy, Ralph, G. Scott, Mason, Sarah, Gouello, Gaëtane, Domenech, Philippe, Buttery, Philip C., Hantraye, Philippe, Tuckwell, Nicola J., Barker, Roger A., Mitrophanous, Kyriacos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157351/
https://www.ncbi.nlm.nih.gov/pubmed/30156440
http://dx.doi.org/10.1089/humc.2018.081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157351/
https://www.ncbi.nlm.nih.gov/pubmed/30156440
http://dx.doi.org/10.1089/humc.2018.081

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