Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway

Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role of LPA in the post-infarct heart remains unkno...

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Detalles Bibliográficos
Autores principales: Yang, Jinjing, Xu, Jiyao, Han, Xuebin, Wang, Hao, Zhang, Yuean, Dong, Jin, Deng, Yongzhi, Wang, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157396/
https://www.ncbi.nlm.nih.gov/pubmed/30283359
http://dx.doi.org/10.3389/fphys.2018.01315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157396/
https://www.ncbi.nlm.nih.gov/pubmed/30283359
http://dx.doi.org/10.3389/fphys.2018.01315

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