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Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway
Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role of LPA in the post-infarct heart remains unkno...
Autores principales: | Yang, Jinjing, Xu, Jiyao, Han, Xuebin, Wang, Hao, Zhang, Yuean, Dong, Jin, Deng, Yongzhi, Wang, Jingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157396/ https://www.ncbi.nlm.nih.gov/pubmed/30283359 http://dx.doi.org/10.3389/fphys.2018.01315 |
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