GLP-2 receptor signaling controls circulating bile acid levels but not glucose homeostasis in Gcgr(−/−) mice and is dispensable for the metabolic benefits ensuing after vertical sleeve gastrectomy

OBJECTIVE: Therapeutic interventions that improve glucose homeostasis such as attenuation of glucagon receptor (Gcgr) signaling and bariatric surgery share common metabolic features conserved in mice and humans. These include increased circulating levels of bile acids (BA) and the proglucagon-derive...

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Detalles Bibliográficos
Autores principales: Patel, Anita, Yusta, Bernardo, Matthews, Dianne, Charron, Maureen J., Seeley, Randy J., Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157461/
https://www.ncbi.nlm.nih.gov/pubmed/29937214
http://dx.doi.org/10.1016/j.molmet.2018.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157461/
https://www.ncbi.nlm.nih.gov/pubmed/29937214
http://dx.doi.org/10.1016/j.molmet.2018.06.006

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