Protocol for the insight study: a randomised controlled trial of single-dose tocilizumab in patients with depression and low-grade inflammation

INTRODUCTION: Observational studies indicate a potentially causal role for interleukin 6 (IL-6), a proinflammatory cytokine, in pathogenesis of depression, but interventional studies based on patients with depression have not been conducted. Tocilizumab, anti-inflammatory drug, is a humanised monocl...

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Detalles Bibliográficos
Autores principales: Khandaker, Golam M, Oltean, Bianca P, Kaser, Muzaffer, Dibben, Claire R M, Ramana, Rajini, Jadon, Deepak R, Dantzer, Robert, Coles, Alasdair J, Lewis, Glyn, Jones, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Mental Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157523/
https://www.ncbi.nlm.nih.gov/pubmed/30244217
http://dx.doi.org/10.1136/bmjopen-2018-025333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157523/
https://www.ncbi.nlm.nih.gov/pubmed/30244217
http://dx.doi.org/10.1136/bmjopen-2018-025333

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