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Protocol for a pilot randomized controlled trial comparing plasma with balanced crystalloid resuscitation in surgical and trauma patients with septic shock

BACKGROUND: Septic shock is a public health problem with high mortality. There remains a knowledge gap regarding the optimal resuscitation fluid to improve clinical outcomes, and the underlying mechanism by which fluids exert their effect. Shock-induced endotheliopathy (SHINE) is thought to be a sha...

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Detalles Bibliográficos
Autores principales: Wei, Shuyan, Kao, Lillian S, Wang, Henry E, Chang, Ronald, Podbielski, Jeanette, Holcomb, John B, Wade, Charles E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157534/
https://www.ncbi.nlm.nih.gov/pubmed/30271882
http://dx.doi.org/10.1136/tsaco-2018-000220