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Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites
The role of DNA methylation patterns in complex phenotypes remains unclear. To explore this question, we adapted our methods for rare variant analysis to characterize genome-wide murine DNA hybridization array to investigate methylation at CpG islands, shores, and regulatory elements. We have applie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157835/ https://www.ncbi.nlm.nih.gov/pubmed/30256791 http://dx.doi.org/10.1371/journal.pone.0203147 |