Cargando…
Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites
The role of DNA methylation patterns in complex phenotypes remains unclear. To explore this question, we adapted our methods for rare variant analysis to characterize genome-wide murine DNA hybridization array to investigate methylation at CpG islands, shores, and regulatory elements. We have applie...
Autores principales: | Uli, Nishanth, Michelen-Gomez, Eduardo, Ramos, Enrique I., Druley, Todd E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157835/ https://www.ncbi.nlm.nih.gov/pubmed/30256791 http://dx.doi.org/10.1371/journal.pone.0203147 |
Ejemplares similares
-
To bind or not to bind - FoxA1 determines estrogen receptor action in breast cancer progression
por: Watters, Rebecca J, et al.
Publicado: (2012) -
Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response
por: Zhong, Mei, et al.
Publicado: (2010) -
Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells
por: Metzakopian, Emmanouil, et al.
Publicado: (2015) -
A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget’s disease
por: Sumitomo, Chiho, et al.
Publicado: (2023) -
FOXA1 is a critical determinant of Estrogen Receptor function and endocrine response
por: Hurtado, Antoni, et al.
Publicado: (2010)