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Tunable activation of therapeutic platelet-rich plasma by pulse electric field: Differential effects on clot formation, growth factor release, and platelet morphology

BACKGROUND: Activation of platelet-rich plasma (PRP) by pulse electric field (PEF) releases growth factors which promote wound healing (e.g., PDGF, VEGF for granulation, EGF for epithelialization). AIMS: To determine after PEF activation of therapeutic PRP: 1) platelet gel strength; 2) profile of re...

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Detalles Bibliográficos
Autores principales: Frelinger, Andrew L., Gerrits, Anja J., Neculaes, V. Bogdan, Gremmel, Thomas, Torres, Andrew S., Caiafa, Anthony, Carmichael, Sabrina L., Michelson, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157860/
https://www.ncbi.nlm.nih.gov/pubmed/30256831
http://dx.doi.org/10.1371/journal.pone.0203557