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Frequent and biased odorant receptor (OR) re-selection in an olfactory placode-derived cell line

We previously characterized a clonal olfactory placode-derived cell line (OP6) as a model system for studying odorant receptor (OR) choice, where individual OP6 cells, similar to olfactory sensory neurons in vivo, transcribe one allele (“monoallelic”) of one OR gene (“monogenic”). The OP6 cell line...

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Detalles Bibliográficos
Autores principales: Noble, J. C., Meredith, Diane, Lane, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157871/
https://www.ncbi.nlm.nih.gov/pubmed/30256852
http://dx.doi.org/10.1371/journal.pone.0204604