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TRUmiCount: correctly counting absolute numbers of molecules using unique molecular identifiers
MOTIVATION: Counting molecules using next-generation sequencing (NGS) suffers from PCR amplification bias, which reduces the accuracy of many quantitative NGS-based experimental methods such as RNA-Seq. This is true even if molecules are made distinguishable using unique molecular identifiers (UMIs)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157883/ https://www.ncbi.nlm.nih.gov/pubmed/29672674 http://dx.doi.org/10.1093/bioinformatics/bty283 |