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Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

Understanding neurological diseases requires tractable genetic systems. Engineered 3D neural tissues are an attractive choice, but how the cellular transcriptomic profiles in these tissues are affected by the encapsulating materials and are related to the human-brain transcriptome is not well unders...

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Detalles Bibliográficos
Autores principales: Tekin, Halil, Simmons, Sean, Cummings, Beryl, Gao, Linyi, Adiconis, Xian, Hession, Cynthia C., Ghoshal, Ayan, Dionne, Danielle, Choudhury, Sourav R., Yesilyurt, Volkan, Sanjana, Neville E., Shi, Xi, Lu, Congyi, Heidenreich, Matthias, Pan, Jen Q, Levin, Joshua Z., Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157920/
https://www.ncbi.nlm.nih.gov/pubmed/30271673
http://dx.doi.org/10.1038/s41551-018-0219-9